Clinical benefits of systemic antibiotics may depend on periodontitis stage
A study(1) on the clinical benefits of systemic antibiotics in periodontitis treatment has been published by the European Federation of Periodontology in the Journal of Clinical Periodontology (JCP).
The EFP S3-level clinical practice guideline emphasises the need to carefully evaluate the benefits and potential risks of prescribing systemic antibiotics as an adjunct to subgingival instrumentation.
The JCP Digest study hypothesised that combining generalised periodontitis stage III and IV with grade C could yield greater benefits from using metronidazole and amoxicillin adjunctively.
The findings indicate that, within certain limitations, patients diagnosed with generalised stage III, grade C periodontitis may experience reduced clinical attachment loss when treated with systemic amoxicillin/metronidazole adjunctively to subgingival instrumentation.